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发布时间 2019-07-26 22:09:02 点击: 8 作者:

阿尔茨海默症预防

此次ACImmune公司融资是为了对公司目前发现的一种新的抗体进行进一步研究,

投资2200万美元以支持公司正在进行的阿尔兹海默症疫苗研究,公司此前发现了一种名为crenezumab的抗体,能够对β淀粉样蛋白体起作用。目前公司正在与Genetech对其进行联合研究;这种抗体的靶点是tau蛋白,该蛋白也被认为是人类阿尔兹海默症的重要诱因。

近年来在阿尔兹海默症研究领域,目前这种抗体已经在动物研究中取得出良好的效果!世界各大医药巨头如强生,更有甚者。礼来等纷纷。

一些生物医药公司甚至退出了该研究领域,

也正因为如此,

一旦该领域取得突破,那么突破的一方将迅速占领这一广阔市场的制高点,ACImmune公司正是看准这一目标。因此在这一领域中投入巨大的人力物力;目前公司正在对这种疫苗的安全性进行考察,详细英文报道:GermanbillionaireDietmarHoppisaddingtohismultimilliondollarwageronACImmu。

theSwissbiotechthatisplayingakeyroleinsomehighprofileAlzheimer'sHopphasbeentheprimaryinvestorbehindthecompany,andtodayhejoinedina$22millionDrounddesignedtofundanewtherapeuticvaccineprogramaimedatthememorywastingACImmuneisn'tbuiltlikemostCEOAndreaPfeiferhasarrangedsomelucrativepartnershipswithGenentech。whichmostnotablyispursuingahighprofilemidstageprogramforcrenezumab,anantibodydiscoveredbytheSwissThatantibodyisdesignedtoworkonamyloidbeta;atoxicproteinthatisimplicatedinthedevelopmentofAlzheimer'sThatpartnershipmoneyhashelpedfuelthecompany'sbasicresearchwo。

theothertangleinthebrainthathasalsobeenimplicatedasatriggerforAlzheimer'ACImmunehasnowraisedatotalof$88millioninventurefunds,

"PfeifertellsFierceBiotechtodayaboutthephosphortauinitiative。

whilethisnewinjectionofcashisspecificallyearmarkedfortheclinicaldevelopmentofanotherantibodythatACImmunehasdiscoveredandsuccessfullytestedinThisnewtherapytargetstau;withhundredsofmillionsmoreinvolvedinitsHopp。anactivebiotechinvestor。hasbeenoneofthecompany'sbiggest"Wehaveexcellentdatafromtoxicology,partofamultiprongedapproachthattheCEOoftheLausannebasedbiotechbelieveswillultimatelyberequiredtoconquerwhathasbeenoneofthemostvexingscientificchallengesinAndanycompanywhichfindsakeytosolvingthecomplexpuzzleofAlzheimer。

addingthat"theanimaldatawere"Theadvanceontauhelpssetsthestageforfuturecombosinvolvingantibodiesforbothtauandamyloidbeta。orownsanypartof。

willstandtoearnablockbusterSofar,though,withfarmorefailurethansuccessinafieldmarkedbysomemightilyexpensivemistakesundertakenbygiantslikeJohnson&JohnsonandEliLily,dozensofAlzheimer'sstudieshavefailedinrecentyears;TheplanatACImmuneistocompleteanearlystagesafetystudyofthisnewvaccineandthenlooktobringinapartner,saysPfeifer;notingtheextraordinarilyhighcostassociatedwithAlzheimer's。

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